Extracellular Signal-Regulated MAP Kinases

A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.

Also Known As:

Extracellular Signal Regulated Kinases; MAP Kinases, Extracellular Signal Regulated; Extracellular Signal Regulated Kinase; Extracellular Signal Regulated MAP Kinase; Extracellular Signal Regulated MAP Kinases; Kinase, ERK MAP; Kinase, Extracellular Signal-Regulated; Kinases, Extracellular Signal-Regulated; MAP Kinase, ERK; Signal-Regulated Kinase, Extracellular; ERK MAP Kinase; ERK MAP Kinases; Extracellular Signal-Regulated Kinase; Extracellular Signal-Regulated Kinases; Extracellular Signal-Regulated MAP Kinase; MAP Kinases, Extracellular Signal-Regulated

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Mitogen-Activated Protein Kinases: 7508
        Extracellular Signal-Regulated MAP Kinases: 3813
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Mitogen-Activated Protein Kinases: 7508
        Extracellular Signal-Regulated MAP Kinases: 3813

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Disease

Drug/Important Bio-Agent (IBA)